By setting aside space for a home office, any small business can be turned into a home business. Get a 1-800 number, an e-mail address and a well-designed Web page, and no one needs to know that your corporate headquarters are in your spare bedroom.
Some high-paying careers are increasingly centered at home, such as home-based physicians who review and evaluate patient cases for health care companies. According to the U.S. Bureau of Labor Statistics, these physicians earn an average of $100,000 a year [source: Goudreau]. Even if you don't hold a doctoral degree, there are virtually unlimited options for running a small business out of your home: business consulting, meeting or event planning, Web-based retail, life coaching, personal training, therapy, dog grooming -- the list goes on and on.